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GHRP-6
GHRP-6 is a synthetic peptide that stimulates growth hormone release through the ghrelin receptor and is studied for its effects on GH production, metabolism, appetite, and recovery.
Quantity: 1
All peptides arrive in powdered form for stability
What is GHRP-6?
GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that belongs to the growth hormone secretagogue family. It was developed to stimulate the release of growth hormone (GH) from the pituitary gland through a pathway distinct from growth hormone–releasing hormone (GHRH). GHRP-6 has been studied for its potential effects on growth hormone production, metabolism, appetite regulation, and recovery processes.
Potential Benefits Shown in Studies
Possible benefits of GHRP‑6:
- Potent Growth Hormone Stimulation
- Increased Appetite via Ghrelin Receptor Activation
- Enhanced Recovery & Tissue Repair
- Cardioprotective & Cytoprotective Properties
- Improved Metabolic Function & Fat Storage Regulation
Mechanisms of Action
GHRP-6 works by:
- Binding to the ghrelin receptor (GHS-R1a), stimulating the pituitary to release growth hormone
- Increasing circulating GH levels, which can influence IGF-1 production and tissue growth
- Promoting protein synthesis and muscle cell repair in animal models
- Modulating metabolic processes such as fat utilization and carbohydrate metabolism
- Stimulating appetite via ghrelin-mimicking effects
- Supporting collagen synthesis and joint health in research settings
Molecular Structure of GHRP-6
Sequence
His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
Molecular Properties
C₄₆H₅₆N₁₂O₆
873.01 g/mol
GHRP-6 Research Highlights
GHRP‑6, a synthetic hexapeptide, is known for its high potency in stimulating growth hormone (GH) secretion via the ghrelin receptor, distinguishing it from GHRH-based pathways.
Source: springer
In rat models, GHRP‑6 administered alongside doxorubicin prevented heart failure and multi-organ damage, boosting antioxidant defenses, preserving mitochondrial integrity, and reducing fibrosis.
Source: frontiers
Studies show that central administration of GHRP‑6 in rats triggers feeding behavior, activating hypothalamic and brainstem regions—even when animals had no access to food.
Source: academic