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IGF-1LR3+GHRP-6
IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1) is a synthetic, extended half-life analog of human IGF-1, a hormone that plays a critical role in muscle growth, repair, and cellular regeneration. The LR3 modification extends IGF-1’s active window from minutes to over 20 hours, enhancing its potential biological effects. GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that stimulates the release of growth hormone (GH) by activating ghrelin receptors. In research settings, combining IGF-1 LR3 and GHRP-6 may influence both direct anabolic signaling (via IGF-1) and indirect anabolic effects through increased GH and IGF-1 production.
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What is IGF-1LR3+GHRP-6?
IGF-1 LR3 (Long Arg3 Insulin-Like Growth Factor-1) is a synthetic, extended half-life analog of human IGF-1, a hormone that plays a critical role in muscle growth, repair, and cellular regeneration. The LR3 modification extends IGF-1’s active window from minutes to over 20 hours, enhancing its potential biological effects. GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that stimulates the release of growth hormone (GH) by activating ghrelin receptors. In research settings, combining IGF-1 LR3 and GHRP-6 may influence both direct anabolic signaling (via IGF-1) and indirect anabolic effects through increased GH and IGF-1 production.
Mechanisms of Action
IGF-1 LR3 + GHRP-6 may work together by:
IGF-1 LR3: Binding to IGF-1 receptors in muscle and connective tissue to stimulate protein synthesis and promote cell growth
GHRP-6: Activating ghrelin receptors (GHS-R1a) to trigger GH release from the pituitary, which in turn increases natural IGF-1 production
Enhancing satellite cell activation in muscle tissue, supporting repair and hypertrophy
Promoting collagen production and connective tissue recovery in research models
Supporting nutrient partitioning, potentially improving muscle-to-fat ratio
Providing both immediate (LR3) and secondary (GH-mediated) IGF-1 pathways for tissue growth and regeneration