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GHRP-2

GHRP-2

GHRP-2 is a synthetic peptide that stimulates growth hormone release through the ghrelin receptor and is known for its potency in boosting GH, supporting recovery, metabolism, and appetite regulation.

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All peptides arrive in powdered form for stability

What is GHRP-2?

GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide in the growth hormone secretagogue family, developed to stimulate the release of growth hormone (GH) from the pituitary gland. Similar to GHRP-6, it acts via the ghrelin receptor but has been shown in studies to be more potent in elevating GH levels. Research has explored its potential effects on growth hormone production, tissue repair, metabolic function, and appetite regulation.

Potential Benefits Shown in Studies

Possible benefits of GHRP‑2

  • Potent Growth Hormone Release
  • Enhanced Muscle Repair & Recovery
  • Improved Metabolism & Fat Utilization
  • Increased Appetite via Ghrelin Activation
  • Support for Anti-Aging & Cellular Regeneration

Mechanisms of Action

GHRP-2 works by:

  • Binding to the ghrelin receptor (GHS-R1a) to stimulate natural GH release from the pituitary
  • Increasing circulating GH and potentially IGF-1 levels, supporting tissue growth and repair
  • Enhancing protein synthesis and collagen production in research models
  • Influencing metabolic pathways, promoting fat utilization while preserving lean mass
  • Stimulating appetite through ghrelin-mimicking activity
  • Supporting recovery of muscles, joints, and connective tissue in animal studies

Molecular Structure of GHRP-2

GHRP-2 molecular structure

Sequence

D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂

Molecular Properties

Formula

C₄₅H₅₅N₉O₆

Weight

817.98 g/mol

GHRP-2 Research Highlights

Studies indicate GHRP-2 produces a stronger GH release than GHRP-6, with a rapid and measurable rise in circulating GH levels.

Source: pubmed

Animal research suggests GHRP-2–induced GH elevation may enhance muscle repair, tendon healing, and collagen synthesis.

Source: pubmed

In animal studies, GHRP‑2 has been shown to suppress pro-inflammatory cytokines like IL‑6 in macrophages and reduce stress hormone release, suggesting systemic immunomodulatory effects.

Source: frontiersin

Its ability to modulate GH release has positioned GHRP‑2 as a research tool for exploring tissue repair, metabolic regulation, cognitive function, bone metabolism, and cardiovascular resilience.

Source: sarasota

Disclaimer: GHRP-2 is not FDA-approved and is classified as a research peptide. This content is intended for educational and informational purposes only.

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